Table 1 Recent studies on paper-based sensors for miRNA detection
From: Advances in paper-based biosensors for point-of-care miRNA detection
Sensor type | Fabrication steps | Linear range | Limit of detection | Target miRNA | Ref |
|---|---|---|---|---|---|
AuNP/RGO Paper Electrochemical Biosensor | Inkjet printing of AuNPs and RGO on paper | Picomolar to nanomolar | 25.71 nM | miR- 155 | [32] |
BRET Paper-Based System | Freeze-dried circular DNA probes and RCA components on paper discs | Femtomolar to picomolar | 2.5fM, 0.8fM, 1.3fM | miR- 500, miR- 21, miR- 155 | [33] |
Gold Inkjet Printing Electrochemical Biosensor | Inkjet printing of gold ink for miR- 21 detection | 0.35fM—100 pM | 0.35fM | miR- 21 | [34] |
Cys/AuNPs Colorimetric Biosensor | Immobilization of cysteamine-capped gold nanoparticles (Cys/AuNPs) on paper disks | 1 pM − 1 nM | 0.5 pM | miR- 21 | [35] |
GONET and Target-Recycled Signal Amplification | Pre-treatment of Whatman filter paper with GONET | Not specified | Not specified | Not specified | [35] |
Impedimetric Detection | Electrode assembly on paper for miRNA detection | Not specified | Not specified | Not specified | [36] |